TABLE 3.
Discrimination (Discrim) and item location parameters of all MDS-UPDRS Parts 2 + 3 items from fitting one IRT model
Items | Item Names | Discrim | 0 to 1 | 1 to 2 | 2 to 3 | 3 to 4 |
---|---|---|---|---|---|---|
2.1 | Speech | 1.235 | 0.668 | 0.588 | 2.017 | 4.146 |
2.2 | Saliva and drooling | 0.870 | 0.292 | 0.717 | 2.332 | 4.432 |
2.3 | Chewing and swallowing | 1.175 | 0.495 | 1.994 | 3.001 | 5.951 |
2.4 | Eating tasks | 1.634 | 0.470 | 0.890 | 2.329 | 3.641 |
2.5 | Dressing | 2.003 | 0.911 | 0.490 | 1.606 | 2.625 |
2.6 | Hygiene | 1.916 | 0.636 | 0.837 | 1.775 | 2.710 |
2.7 | Handwriting | 1.280 | 1.279 | 0.392 | 1.568 | 2.872 |
2.8 | Doing hobbies and other activities | 1.504 | 0.812 | 0.404 | 1.445 | 2.436 |
2.9 | Turning in bed | 1.714 | 0.701 | 0.722 | 1.718 | 2.588 |
2.10 | Tremor | 0.492 | 2.259 | 0.871 | 3.735 | 6.712 |
2.11 | Getting out of bed | 1.990 | 0.880 | 0.379 | 1.359 | 2.254 |
2.12 | Walking and balance | 1.798 | 1.077 | 0.461 | 1.250 | 2.374 |
2.13 | Freezing | 1.385 | 0.009 | 0.927 | 1.801 | 3.132 |
3.1 | Speech | 1.633 | −0.87 | 0.71 | 2.127 | 3.646 |
3.2 | Facial expression | 1.610 | 1.392 | 0.244 | 1.864 | 3.441 |
3.3a | Rigidity—neck | 1.363 | 0.559 | 0.780 | 2.220 | 3.788 |
3.3b | Rigidity—RUE | 1.302 | 1.113 | 0.451 | 2.294 | 4.388 |
3.3c | Rigidity—LUE | 1.340 | 0.978 | 0.486 | 2.176 | 4.133 |
3.3d | Rigidity—RLE | 1.488 | 0.596 | 0.698 | 2.219 | 3.865 |
3.3e | Rigidity—LLE | 1.508 | 0.551 | 0.658 | 2.100 | 3.756 |
3.4a | Finger tapping—right hand | 1.796 | 1.300 | 0.137 | 1.412 | 3.029 |
3.4b | Finger tapping—left hand | 1.922 | 1.221 | 0.003 | 1.204 | 2.795 |
3.5a | Hand movements—right hand | 2.017 | 1.008 | 0.281 | 1.530 | 2.991 |
3.5b | Hand movements—left hand | 1.947 | 1.025 | 0.285 | 1.514 | 3.065 |
3.6a | Pronation-supination—right hand | 1.867 | 1.029 | 0.298 | 1.548 | 2.979 |
3.6b | Pronation-supination—left hand | 1.841 | 1.084 | 0.152 | 1.349 | 2.804 |
3.7a | Toe tapping—right foot | 1.945 | 0.987 | 0.321 | 1.459 | 2.738 |
3.7b | Toe tapping—left foot | 1.953 | 1.041 | 0.146 | 1.243 | 2.524 |
3.8a | Leg agility—right leg | 2.184 | 0.735 | 0.511 | 1.600 | 2.811 |
3.8b | Leg agility—left leg | 2.224 | 0.776 | 0.382 | 1.410 | 2.662 |
3.9 | Arising from chair | 2.220 | 0.003 | 0.974 | 1.666 | 2.441 |
3.10 | Gait | 2.243 | 1.102 | 0.332 | 1.472 | 2.509 |
3.11 | Freezing of gait | 1.717 | 0.524 | 1.289 | 2.214 | 2.938 |
3.12 | Postural stability | 1.878 | 0.220 | 0.608 | 1.237 | 2.529 |
3.13 | Posture | 1.868 | 1.023 | 0.370 | 1.585 | 2.906 |
3.14 | Global spontaneity of movement | 2.202 | 1.221 | 0.079 | 1.222 | 2.629 |
3.15a | Postural tremor—right hand | 0.532 | 0.525 | 3.832 | 6.903 | 11.149 |
3.15b | Postural tremor—left hand | 0.601 | 0.517 | 3.573 | 6.505 | 9.943 |
3.16a | Kinetic tremor—right hand | 0.517 | 1.168 | 4.782 | 8.418 | 12.139 |
3.16b | Kinetic tremor—left hand | 0.523 | 0.970 | 4.315 | 7.949 | 11.264 |
3.17a | Rest tremor amplitude—RUE | 0.453 | 0.884 | 3.096 | 6.056 | 10.336 |
3.17b | Rest tremor amplitude—LUE | 0.542 | 0.910 | 2.883 | 5.664 | 9.312 |
3.17c | Rest tremor amplitude—RLE | 0.529 | 2.630 | 4.774 | 7.785 | 11.998 |
3.17d | Rest tremor amplitude—LLE | 0.599 | 2.655 | 4.482 | 7.154 | 10.553 |
3.17e | Rest tremor amplitude—lip/jaw | 0.674 | 3.083 | 5.089 | 7.330 | 9.221 |
3.18 | Constancy of rest tremor | 0.365 | 0.627 | 1.901 | 4.213 | 6.762 |
Note: 11 tremor items with low and moderate discrimination parameters are in boldface.
Abbreviations: MDS-UPDRS, The Movement Disorder Society Unified Parkinson’s Disease Rating Scale; IRT, item response theory; RUE: right upper extremity; LUE, left upper extremity; RLE, right lower extremity; LLE, left lower extremity.