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. 2023 Mar 6;29(3):646–655. doi: 10.1038/s41591-023-02216-8

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — The cohort comprises 125 patients (n = 250 tumors) sBBCs and both immune infiltration and concordance status of the pair available (n = 125 and 248 respectively for intratumoral TILs). A. stromal TIL levels; B. Comparison of the absolute difference of between the stromal TIL levels of the left and the right side; Lower and upper bars represent the first and third quartile, respectively, the medium bar is the median, and whiskers extend to 1.5 times the inter-quartile range. C. Intratumoral TIL levels; D. Comparison of the absolute difference of between the intratumoral TIL levels of the left and the right side. Lower and upper bars represent the first and third quartile, respectively, the medium bar is the median, and whiskers extend to 1.5 times the inter-quartile range. Statistical tests were Wilcoxon tests (Extended Data Fig. 2B, D) and are two-sided. Abbreviations: str TIL, stromal tumor infiltrating lymphocytes; TNBC: triple negative breast cancer.