Extended Data Fig. 7. Cell-specific Ptger3 knockout attenuates behavioral responses to sublethal influenza A doses.

Phox2b-Cre; flox-Ptger3 mice (red) or flox-Ptger3 mice (black) were infected with sublethal doses of influenza A virus (top: 10⁵ EID₅₀ or LD₂₁, bottom: 10^5.5 EID₅₀ or LD₃₉) and monitored daily as indicated, mean ± sem, n: 6 mice per group, **p < 0.005, ***p < 0.0005 by two-tailed unpaired t-test as detailed in Fig. 1 for behavior/physiology analysis, *p < 0.05, ns: not significant by a log-rank (Mantel-Cox) test for survival analysis. p values top to bottom left: <0.0001, <0.0001, <0.0001, 0.0002, 0.4524; right: <0.0001, <0.0001, <0.0001, 0.0002, 0.0155.

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