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. 2023 Mar 9;14:1133423. doi: 10.3389/fphys.2023.1133423

TABLE 1.

Anthracyclines, therapeutic use and maximum recommended cumulative dose.

Anthracycline Clinical activity Maximum cumulative dose
Daunorubicin Treatment of acute myeloid leukemia, acute lymphoblastic leukemia, chronic myelogenous leukemia, and Kaposi’s sarcoma 550 mg/m2
Doxorubicin Treatment of breast cancer, bladder cancer, stomach cancer, lung cancer, acute lymphocytic leukemia, and Kaposi’s sarcoma 550 mg/m2
Epirubicin Treatment of breast cancer, stomach cancer, lung cancer, urinary tract carcinoma, and ovarian carcinoma 900 mg/m2
Idarubicin Treatment of acute myeloid leukemia, acute lymphoblastic leukemia, and chronic myelogenous leukemia 150 mg/m2
Valrubicin Treatment of bladder cancer 800 mg/m2