Table 2.
IVF Lab parameters and embryonic outcomes per cycle
| FMR1 | Controls | P value | |
|---|---|---|---|
| Lab parameters | |||
| No. of oocytes injected | 8.98 ± 7.02 | 12.25 ± 7.19 | < 0.001 |
| Fertilization rate % | 60.6% 2350/3878 | 58.2% 1470/2526 | 0.057 |
| No. of embryos biopsied | 4.86 ± 3.59 | 6.67 ± 4.22 | < 0.001 |
| Biopsy rate % | 79.2% 1862/2350 | 83.1% 1221/1470 | 0.004 |
| Embryonic outcomes | |||
| No. of healthy embryos | 2 ± 1.78 | 2.77 ± 2.45 | < 0.001 |
| No. of embryos that inherited the mutated allele | 2.05 ± 1.86 | 2.92 ± 2.06 | < 0.001 |
| No. of undiagnosed embryos | 0.4 ± 0.78 | 0.51 ± 0.75 | 0.137 |
| No. of frozen embryos | 0.54 ± 1.72 | 1.34 ± 3.73 | 0.007 |
| No. of embryos transferred | 1.43 ± 1.17 | 1.6 ± 1.21 | 0.117 |
Data is presented as mean ± std. deviation or as rate (%); No. = number
The mean number of embryos undergoing biopsy per patient was 20.92 ± 20.36 and 16.96 ± 14.48 for FMR1 and controls, respectively, p = 0.152