Table 3.
DEPs in FF-EVs of PCOS and normal controls
| UniProtKB-AC | Protein name | Foldchange | FDR | p value | |
|---|---|---|---|---|---|
| P28161 | GSTM2 | Glutathione S-transferase Mu 2 | 2.258 | 0.96 | 0.011 |
| Q8IVG5 | SAMD9L | Sterile alpha motif domain-containing protein 9-like | 2.209 | 0.96 | 0.011 |
| Q9BYE9 | CDHR2 | Cadherin-related family member 2 | 1.977 | 0.96 | 0.004 |
| P35542 | SAA4 | Serum amyloid A-4 protein | 1.734 | 0.99 | 0.047 |
| Q13822 | ENPP2 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 1.516 | 0.96 | 0.019 |
| O95932 | TGM3L | Protein-glutamine gamma-glutamyltransferase 6 | 1.514 | 0.47 | 0.000 |
| P22105 | TENX | Tenascin-X | 1.503 | 0.99 | 0.048 |
| P00748 | FA12 | Coagulation factor XII | 1.483 | 0.96 | 0.009 |
| O95497 | VNN1 | Pantetheinase | 1.471 | 0.96 | 0.023 |
| Q15043 | S39AE | Zinc transporter ZIP14 | 0.651 | 0.97 | 0.035 |
| O15270 | SPTC2 | Serine palmitoyltransferase 2 | 0.649 | 0.96 | 0.026 |
| O75976 | CBPD | Carboxypeptidase D | 0.641 | 0.96 | 0.006 |
| O75396 | SC22B | Vesicle-trafficking protein SEC22b | 0.637 | 0.96 | 0.013 |
| P0DOY2 | IGLC2 | Immunoglobulin lambda constant 2 | 0.630 | 0.96 | 0.011 |
| Q16850 | CP51A | Lanosterol 14-alpha demethylase | 0.627 | 0.98 | 0.045 |
| Q96K37 | S35E1 | Solute carrier family 35 member E1 | 0.616 | 0.96 | 0.021 |
| P37058 | DHB3 | Testosterone 17-beta-dehydrogenase 3 | 0.616 | 0.96 | 0.023 |
| P07099 | HYEP | Epoxide hydrolase 1 | 0.614 | 0.96 | 0.018 |
| Q3KR37 | GRAMD1B | GRAM domain-containing protein 1B | 0.612 | 0.90 | 0.003 |
| Q9UBV2 | SE1L1 | Protein sel-1 homolog 1 or Suppressor of lin-12-like protein | 0.611 | 0.98 | 0.044 |
| P21817 | RYR1 | Ryanodine receptor 1 or Skeletal muscle calcium release channel | 0.608 | 0.98 | 0.041 |
| Q15392 | DHC24 | Delta(24)-sterol reductase | 0.607 | 0.96 | 0.004 |
| Q13530 | SERC3 | Serine incorporator 3 | 0.606 | 0.96 | 0.014 |
| P51648 | AL3A2 | Fatty aldehyde dehydrogenase | 0.604 | 0.96 | 0.007 |
| P21964 | COMT | Catechol O-methyltransferase | 0.595 | 0.96 | 0.026 |
| A0M8Q6 | IGLC7 | Immunoglobulin lambda constant 7 | 0.594 | 0.97 | 0.028 |
| Q14764 | MVP | Major vault protein | 0.587 | 0.96 | 0.019 |
| Q8N3P4 | VPS8 | Vacuolar protein sorting-associated protein 8 homolog | 0.586 | 0.97 | 0.033 |
| P02792 | FRIL | Ferritin light chain | 0.579 | 0.97 | 0.030 |
| P01834 | IGKC | Immunoglobulin kappa constant | 0.560 | 0.98 | 0.039 |
| Q15738 | NSDHL | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | 0.518 | 0.96 | 0.020 |
| Q9UBM7 | DHCR7 | 7-Dehydrocholesterol reductase | 0.43 | 0.96 | 0.024 |
FDR, false discovery rate