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. 2023 Mar 9;14:1114596. doi: 10.3389/fimmu.2023.1114596

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Copyright © 2023 Zhang, Zhang, Liu, Wu, Wang, Li, Huang, Qiu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of EE treatment on open field test in CCH mice. (A) Movement track of mice. (B) Heat map of mouse movement. (C-K) Behavior analysis of open field test, including total distance (C), distance in center (D), distance in periphery (E), center zone entries (F), periphery zone entries (G), latency to center (H), latency to periphery (I), movement time in center (J) and movement time in periphery (K). Values represent the mean ± s.d. ^aP < 0.05 vs. Sham; ^bP < 0.05 vs. CCH group (n = 6).