Fig. 3.

Mean log colony forming unit (CFU) per lung versus time profiles in group receiving either no treatment (Control, black circle), a CIP solution by IV administration (open triangle), or CIP-Cu²⁺ microparticles by IT administration (open square). The CIP dose was 2.5 mg/kg for all animals. Data points represent averaged values ± standard deviation (SD) of 4–5 individual measurements. Statistical analyses were performed using a one-way ANOVA and Tukey's multiple comparisons test (** mean P ≤ 0.01).