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GST–MT prefers CpG sequences in site selection experiments. Site selection experiments (Materials and Methods) were performed with oligonucleotides containing a core of 26 random nt. The sequences of 19 clones with high affinity to GST–MT are shown. The vertical lines indicate the extent of the original randomly designed sequence with flanking nucleotides given if they contribute to form a CpG dinucleotide. CpG sequences are boxed.
