Fig. 3. A) Workflow of pretargeted autoradiography. B) Pretargeted autoradiography images for selected Tzs. C) Brain time-activity curves for selected Tzs. D) Structures of Tzs selected for further evaluation. E) Ranking of evaluated Tzs by in vitro contrast and in vivo brain uptake kinetics. Tzs selected for further evaluation are marked with filled symbols, relative rankings (in vitro/in vivo) are shown in parentheses. In vitro contrast for [18F]18 was estimated by regression (see ESI† Section S7).
