Fig. 3. TSNE maps for reactions in USPTO 50K and Reaxys test for 9 reaction classes. The points which lie close together represent similar reactions. The absolute coordinates of the points have no physical meaning. On top and on the right of each graph, the estimates of the distribution of the corresponding coordinates are shown. The functional group addition (FGA) class is not shown due to the low number of reactions of this class in the Reaxys test.