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. 2023 Mar 17;31:101652. doi: 10.1016/j.tranon.2023.101652

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© 2023 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 2 — CircRNA expression profile in CRC and control group and screening of differentially-expressed circRNAs.(A) Cluster analysis of the expression of the circRNAs by deep sequencing. The result shows the top 30 differentially-expressed circRNAs. (B) Volcano plot showing fold differences in gene expression. The red dots represent the upregulated or downregulated genes. (C) Cluster analysis of the differentially-expressed circRNAs in the GSE126094 dataset. The result shows the top 30 circRNAs. (D) Venn diagram of the differentially-expressed circRNAs obtained by clustering analysis. The data were analyzed with P-value < 0.05 and LogFC >2 as the threshold. Cluster analysis and Volcano plot analysis were performed using the gplots package in R.