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. 2023 Mar 17;31:101652. doi: 10.1016/j.tranon.2023.101652

Fig. 3.

Fig 3

Expression level of circGAPVD1 and its efficacy as a diagnostic marker (A) Differential expression of four circRNAs in 35 paired CRC and healthy controls. The graphs were generated using GraphPad Prism software (version 8.0). (B) ROC curve analysis for the diagnostic ability of the four circRNAs in 35 paired CRC and healthy controls. (C) Differential expression of circGAPVD1 in 78 paired CRC and healthy controls with P-value < 0.001. (D) ROC curve analysis for the diagnostic ability of circGAPVD1 in 78 paired CRC and healthy controls. (E) The expression of circGAPVD1 examined using PCR and agarose gel electrophoresis. circGAPVD1 could be amplified by divergent primers in the complementary DNA (cDNA) but not genomic DNA (gDNA). 18S rRNA was used as a positive control. Results are shown as mean ± s.d, *p<0.05; **p < 0.01, ***p < 0.001, n.s., no significance.