Fig. 5. CHs for nerve and muscle repair. (A) The growth of neurites in the hydrogel loaded with 20 μg mL−1 SWCNTs increased by 3.3 times. Reproduced from ref. 30 with the permission of Elsevier, copyright 2016. (B) Collagen/hyaluronic acid hydrogels loaded with bone marrow mesenchymal stem cells (BMSCs) and conductive antioxidant bifunctional PPy nanoparticles protect BMSCs from oxidative damage, and promote nerve regeneration and functional recovery through a synergy between conductivity and electrical stimulation. Reproduced from ref. 88 with the permission of American Chemical Society, copyright 2021. (C) CNT-based injectable and conductive cardiac patches. (a) The methacrylated elastin-gelatin cryogel cardiac patches loaded with CNTs was prepared by low temperature crosslinking of double bonds. And the patches support a compression force of about 400 N at 95% strain. (b) The injection diagram of the patches and the patches injected into the lesion site. (c) After 4 weeks of treatment, the representative multi-layer cross-section of the pig heart in the myocardial infarction (MI) control group, human cardiomyocyte (HCM) injection treatment, EGC20 patch implant treatment, and the HCM-EGC20 cardiac patch (HECP) treatment group. Statistical data of the (d) anterior wall thickness and (e) scar thickness of the left ventricle in different treatment groups. Reproduced from ref. 33 with the permission of Springer Nature, copyright 2021.
