Fig. 7. CHs for skin repair. (A) The selenoviologen-appendant polythiophene (SeV2+-PT)-containing polyacrylamide hydrogels rapidly generate renewable and stable ROS, which quickly and efficiently kills bacteria (6 s), and shortens the healing time of infected wounds to 7 days. Reproduced from ref. 90 with the permission of Wiley-VCH, copyright 2021. (B) Adhesion-enhanced phenylboronic acid, benzaldehyde bifunctional polyethylene glycol-co-poly(glycerol sebacic acid)/dihydrocaffeic acid and l-arginine co-grafted chitosan/polydopamine-coated reduced GO/Metformin (PEGS-PBA-BA/CS-DA-LAG/GO/Met) hydrogels with pH/glucose dual stimuli-responsive metformin release ability show a promoting effect on the healing of chronic athletic type II diabetic foot wounds. (a) Schematic diagram of hydrogel preparation and application. (b) Adhesion and (c) pH/glucose dual stimuli-responsive metformin release ability of the CHs. (d) Representative images of the rats' feet in the experimental and control groups during repair. Reproduced from ref. 21 with the permission of American Chemical Society, copyright 2022.
