Table 4.
Meta-analysis results of Treatment-related AEs.
| Outcomes | Studies | Participants | Heterogeneity test results | Effect model | Meta-analysis results | ||
|---|---|---|---|---|---|---|---|
| P | I2 | 95%CI | P | ||||
| Rash | 5 | 620 | 0.29 | 19% | Fixed | 1.73 [1.08, 2.77] | 0.02 |
| Pruritus | 4 | 463 | 0.83 | 0% | Fixed | 1.71 [0.83, 3.53] | 0.14 |
| Pain | 4 | 478 | 0.17 | 41% | Fixed | 1.27 [0.87, 1.84] | 0.22 |
| Fever | 2 | 240 | 0.97 | 0% | Fixed | 1.36 [0.82, 2.24] | 0.23 |
| Diarrhea | 5 | 620 | 0.83 | 0% | Fixed | 1.13 [0.82, 1.56] | 0.46 |
| Fatigue | 5 | 620 | 0.51 | 0% | Fixed | 1.53 [1.17, 2.01] | 0.002 |
| Nausea | 5 | 620 | 0.45 | 0% | Fixed | 1.82 [1.26, 2.62] | 0.001 |
| Decreased appetite | 4 | 463 | 0.82 | 0% | Fixed | 1.42 [0.88, 2.30] | 0.15 |
| Hypothyroidism | 5 | 620 | 0.81 | 0% | Fixed | 1.32 [0.82, 2.12] | 0.26 |
| Hyperthyroidism | 2 | 251 | 0.62 | 0% | Fixed | 1.67 [0.22, 12.52] | 0.62 |