Fig. 7.

Correlating cortical metrics to behavior outcomes. (a) Forelimb asymmetry, assessed with the cylinder test, calculated as a change in impaired forelimb use from pre-stroke, right: recovery of individual mice at week 4. (b) Left: reference image showing outlines of pre-stroke forelimb region and stroke core at 1 week, middle: correlation between overlap of forelimb and stroke with forelimb asymmetry at week 4, right: correlation between stroke area and forelimb asymmetry at week 4. (c) Left: correlation of evoked responses of GCaMP and HbT, middle: correlation between response magnitude at week 1 for GCaMP and HbT with forelimb asymmetry at week 4, right: correlation between the correlation coefficient of evoked responses at week 1 and forelimb asymmetry at week 4. (d) Left: correlation coefficient between measured HbT and HbT predicted by convolving GCaMP and IRF, right: correlation between neurovascular coupling correlation coefficient at week 1 and forelimb asymmetry at week 4. (e) Correlation between power of GCaMP and HbT in frequency band 0.15–0.3 Hz in the ipsilesional and contralesional hemispheres and forelimb asymmetry at week 4. (f) Correlation between resting state interhemispheric connectivity and forelimb asymmetry at week 4.