TABLE 1.

ROC of the key metabolites based on RF and SVM.

Group	Metabolites	ROC (AUC)	Trend
HV vs. CV	L-allo-Isoleucine	0.92	down
	L-Leucine	0.92	down
	N-Acetyl-Asp-Glu	1.00	up
	Lysine Butyrate	0.98	down
	L-Thyroxine	0.94	down
	O-Aceyl-L-Serine	0.92	down
	Lysopc 20–0	1.00	up
	cis-4-Hydroxy-D-proline	0.94	down
	L-Octanoylcarnitine	0.98	down
HA vs. CA	Lysopc 16–1	1.00	down
	Imatinib	1.00	down
	D-Mannose	1.00	down
	4-Hydroxyphenylpyruvate	1.00	down
	Oleoylcarnitine	1.00	down
	Nicotinate ribonucleoside	0.98	down
	Arachidonoylcarnitine	1.00	down
	L-(−)-Glyceric acid	1.00	up
	7-Ketocholesterol	1.00	down
	Oxidized glutathione	0.96	down
	glutathione disulfide	0.96	down
	Dehydrocholic acid	0.98	down