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. Author manuscript; available in PMC: 2023 Jun 10.
Published in final edited form as: Circ Res. 2022 Jun 9;130(12):1906–1925. doi: 10.1161/CIRCRESAHA.122.320257

Table 3:

Phenotype-based characterization of proposed hypertension-associated HFpEF models.

Angiotensin II DOCA/UNX/Salt SAUNA
Systemic hypertension Y (dose dependent) Y (species dependent) Y
Exercise intolerance Y (strain dependent) N/A Y
Pulmonary congestion Y (strain dependent) N Y
Diastolic dysfunction Y Y Y
LV concentric hypertrophy Y (strain dependent) Y Y

Y = yes. N = no. N/A = not available.