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. 2023 Feb 21;61(3):e01859-22. doi: 10.1128/jcm.01859-22

FIG 1.

FIG 1

(A) Biomarker and mycological test dynamics in patients with probable COVID-19-associated pulmonary aspergillosis (CAPA) from Graz, Austria. (B) Biomarker dynamics in patients with probable CAPA from Cardiff, United Kingdom. Day 0 is defined as the day of the first Karius test. Blue plus sign, positive mycological test results (GM cutoffs >1.0 in BALF and >0.5 in serum; BDG cutoff ≥80 pg/mL); red diamond, negative mycological test results; black inverted triangle, day of patient death. Yellow background indicates diagnostic test results obtained during mold-active antifungal therapy. The red bar and arrow describe a time period of negative test results, with vertical black bars indicating the exact days of testing. BALF, bronchoalveolar lavage fluid; BDG, 1,3-β-d-glucan; GM, galactomannan; NBL, nondirected bronchial lavage; ODI, optical density index.