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. 2023 Jan 9;120(1-2):3–10. doi: 10.3238/arztebl.m2022.0377

eTable 1. Overview of new and identified systematic reviews and GRADE tables.

Review on Firstround? Second round? GRADE table? No. of GRADE tables Place of entry in expert material
From: PIM Austria—project report
PPI No Yes Second round 1 A02BC PPI
Benzodiazepines No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Alpha blockers No Yes Second round 1 G04CA alpha-adrenoceptor antagonists
Comment: Not entered for individual substances
Ginkgo biloba No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Anticholinergic urologics and beta-3-adrenoceptor agonists No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Imidazoline receptor agonists No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Tramadol No Yes Second round 1 N02AX02 Tramadol
Sulfonylureas No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Z substances No No No
Comment: Irrelevant in second round due to lack of discrepancy between review and expert assessment
Pregabalin No Yes Second round 1 N03AX16 pregabalin
Aldosterone antagonists No Yes Second round 1 C03DA aldosterone antagonists
Comment: Not entered for individual substances being evaluated
From: generic review on aging
Anabolic steroids after hip fracture Yes No First round 1 G03BA03 testosterone
Second-generation antipsychotics: severe side effects Yes Yes First round
Second round
1 N05A antipsychotics
Second-generation antipsychotics: mortality
Comment: Not entered for individual substances being evaluated
Antibiotics in urinary tract infections Yes Yes First round
Second round
1 J01 antibiotics for systemic use
Comment: Not entered for individual substances being evaluated
Laxatives and iatrogenic falls Yes Yes First round
Second round
1 A06A medications to treat constipation
Comment: Not entered for individual substances being evaluated
Antihistamines and falls/fractures Yes Yes First round
Second round
1 R06A antihistamines for systemic use
Comment: Not entered for individual substances being evaluated
Atypical antipsychotics BPSD Yes
(risperidone)
Yes
(risperidone)
First round
Second round
1 N05AX08 risperidone
Antidepressants in patients aged ≥ 65 years Yes
(duloxetine)
Yes
(duloxetine)
First round
Second round
1 N06AX21 duloxetine
From: PRIMA-eDS and update/new research
DOAC Yes
(text form)
No No B01AA vitamin-K antagonists
Comment: Not entered for individual substances being evaluated
DPP-4 Yes
(text form)
Yes Second round 2 A10BH DPP-4 inhibitors
Comment: Two GRADE PDFs, one for each control
From: PRIMA-eDS
Beta-blockers Yes Yes First round
Second round
2 C07A beta-blockers
Comment: Not entered for individual substances being evaluated
Two GRADE PDFs, one for each control
Metformin Yes No First round 5 A10BA02 metformin
Comment: Five GRADE PDFs, one for each control
Total 21

BPSD, Behavioral and psychological symptoms of dementia; DOAC, direct oral anticoagulants; DPP-4, dipeptidylpeptidase-4; PPI, proton pump inhibitors