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. 2023 Feb 21;15(2):e35261. doi: 10.7759/cureus.35261

Table 3. Clinical characteristics and outcome of 540 patients infected with major variants (n = 540).

  BA.2.10* BA.2.38* BA.2.75* BA.5* BQ.1 XBB* Grand total
Total number of cases with history available
  17 (53.13%) 21 (46.67%) 374 (64.37%) 18 (48.65%) 10 (66.67%) 100 (58.14%) 540 (61.22%)
History of previous COVID-19 infection, p-value = 0.259
  01 (5.88%) 03 (14.29%) 51 (13.64%) 00 (00%) 01 (10%) 15 (15%) 71 (13.15%)
Symptom status at the time of sample collection, p-value = 0.071
Asymptomatic 03 (17.65%) 01 (4.76%) 28 (7.49%) 00 (00%) 03 (30%) 11 (11.%) 46 (8.52%)
Symptomatic 14 (82.35%) 20 (95.24%) 346 (92.51%) 18 (100%) 07 (70%) 89 (89%) 494 (91.48%)
Presence of comorbidity, p-value = 0.145
No comorbidity 17 (100%) 15 (71.43%) 334 (89.30%) 17 (94.44%) 10 (100%) 85 (85%) 478 (88.52%)
Presence of one condition 00 (00%) 05 (23.81%) 27 (7.22%) 01 (5.56%) 00 (00%) 11 (11%) 44 (8.15%)
Presence of two or more conditions 00 (00%) 01 (4.76%) 13 (3.48%) 00 (00%) 00 (00%) 04 (4%) 18 (3.33%)
Initial presenting symptoms
Fever 08 (57.14%) 16 (80%) 277 (80.06%) 13 (72.22%) 05 (71.43%) 65 (73.03%) 384 (77.73%)
Cough 05 (35.71%) 13 (65%) 146 (42.20%) 07 (38.89%) 04 (57.14%) 34 (38.20%) 209 (42.31%)
Fatigue/Weakness 00 (00%) 02 (10%) 78 (22.54%) 02 (11.11%) 01 (14.29%) 10 (11.24%) 93 (18.83%)
Myalgia 03 (21.43%) 00 (00%) 74 (21.39%) 01 (5.56%) 02 (28.57%) 13 (14.61%) 93 (18.83%)
Cold and rhinorrhea 07 (50%) 06 (30%) 163 (47.11%) 11 (61.11%) 03 (42.86%) 47 (52.81%) 237 (47.98%)
Headache 00 (00%) 02 (10%) 26 (7.51%) 00 (00%) 02 (28.57%) 10 (11.24%) 40 (8.10%)
Diarrhea 00 (00%) 00 (00%) 05 (1.45%) 02 (11.11%) 00 (00%) 03 (3.37%) 10 (2.02%)
Breathlessness 00 (00%) 02 (10%) 22 (6.36%) 00 (00%) 01 (14.29%) 06 (6.74%) 31 (6.28%)
Vomiting 00 (00%) 00 (00%) 09 (2.60%) 00 (00%) 00 (00%) 02 (2.25%) 11 (2.42%)
Sore throat 01 (7.14%) 01 (5%) 15 (4.34%) 01 (5.56%) 02 (28.57%) 16 (17.98%) 36 (7.29%)
Skin rash 00 (00%) 00 (00%) 03 (0.87%) 00 (00%) 00 (00%) 00 (00%) 03 (0.61%)
Chest pain 00 (00%) 00 (00%) 01 (0.29%) 00 (00%) 00 (00%) 00 (00%) 01 (0.20%)
Loss of taste 00 (00%) 00 (00%) 02 (0.58%) 00 (00%) 00 (00%) 02 (2.25%) 04 (0.81%)
Loss of smell 00 (00%) 00 (00%) 02 (0.58%) 00 (00%) 00 (00%) 01 (1.12%) 03 (0.61%)
Type of quarantine, p-value = 0.163
Home quarantine 16 (94.12%) 14 (66.67%) 280 (74.87%) 15 (83.33%) 09 (90%) 80 (80%) 414 (76.67%)
Institutional quarantine/required hospitalization 01 (5.88%) 07 (33.33%) 94 (25.13%) 03 (16.67%) 01 (10%) 20 (20%) 126 (23.33%)
Treatment, p-value = 0.067
No treatment taken 03 (17.65%) 00 (00%) 10 (2.67%) 00 (00%) 00 (00%) 04 (4%) 17 (3.15%)
Need for conservative treatment 13 (76.47%) 17 (80.95%) 330 (88.24%) 18 (100%) 10 (100%) 87 (87%) 475 (87.96%)
Need for supplemental oxygen 01 (5.88%) 04 (19.05%) 27 (7.22%) 00 (00%) 00 (00%) 05 (5%) 37 (6.85%)
Low-flow oxygen 01 (100%) 03 (75%) 23 (85.18%) 00 (00%) 00 (00%) 04 (80%) 31 (83.78%)
Intubation 00 (00%) 01 (25%) 04 (14.82%) 00 (00%) 00 (00%) 01 (20%) 06 (16.22%)
Need for antiviral agents/steroids or immunomodulatory drugs 00 (00%) 00 (00%) 07 (1.87%) 00 (00%) 00 (00%) 04 (4%) 11 (2.04%)
The outcome of disease, p-value = 0.495
Survived 17 (100%) 21 (100%) 362 (96.79%) 18 (100%) 10 (100%) 96 (96%) 524 (97.04%)
Dead 00 (00%) 00 (00%) 12 (3.21%) 00 (00%) 00 (00%) 04 (4%) 16 (2.96%)
Vaccination status, p-value = 0.181
Vaccinated with at least one dose 13 (76.47%) 18 (85.71%) 341 (91.18%) 15 (83.33%) 10 (100%) 94 (94%) 491 (90.93%)
Single dose 00 (00%) 00 (00%) 15 (4.40%) 00 (00%) 00 (00%) 02 (2.13%) 17 (3.46%)
Two doses 11 (84.62%) 16 (88.89%) 238 (69.79%) 11 (73.33%) 06 (60%) 68 (72.34%) 329 (73.27%)
Booster dose 02 (15.38%) 02 (11.11%) 88 (25.81%) 04 (26.67%) 04 (40%) 24 (25.53%) 104 (23.16%)
Not vaccinated 04 (23.53%) 03 (14.29%) 28 (7.49%) 03 (16.67%) 00 (00%) 03 (3%) 41 (7.59%)
Data not available 00 (00%) 00 (00%) 05 (1.34%) 00 (00%) 00 (00%) 03 (3%) 08 (1.48%)