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. 2022 Dec 20;2(12):1669–1683. doi: 10.1158/2767-9764.CRC-22-0350

FIGURE 7.

FIGURE 7

A TP63γ minigene recapitulates the PTBP1-dependent regulation of exon γ inclusion. A, Structure of the TP63 minigene stably transfected in HaCaT cells. β-globin gene sequences are shown in orange, TP63 gene sequences are shown in green. B, qRT-PCR quantification of PTBP1, and the RNA isoforms produced from the TP63 minigene after siRNA-mediated PTBP1 depletion. C, Delta PSI are computed as the fold difference between test and siCTRL as the reference condition. In all panels, n = 6; *, P < 0.05; **, P < 0.01; ***, P < 0.001; Dunnett test.