TABLE 2.
Effect of curcumin on the histopathological scoring for spinal cord changes, induced by diabetes.
| Control (n = 6) | Diabetic (n = 6) | Diabetic + Curcumin (n = 6) | H value | p-value | |
| Shrinkage of soma | 0 (0–0) A |
2 (1.25–2) B |
1 (0–1) A |
41.466 | <0.0005 |
| Neurons with pyknotic nuclei | 0 (0–0) A |
2 (1–2) B |
1 (0–1) C |
37.135 | <0.0005 |
| Axon degeneration | 0 (0–0.75) A |
2 (1.25–2) B |
1 (0–1) A |
37.098 | <0.0005 |
| Inflammatory cell infiltrate | 0 (0–1) A |
2 (1.25–2) B |
1 (0–1) A |
35.871 | <0.0005 |
| Focal bleeding | 0 (0–0.75) A |
2 (1.25–2) B |
1 (0–1) A |
38.640 | <0.0005 |
| Score | 1 (1–1.75) A |
9 (8–9) B |
3.5 (3–4.75) C |
52.100 | <0.0005 |
Results are presented as median and interquartile range. The p-value was determined by the Kruskal–Wallis H test; different letters = statistically significant difference. Significant p-values (≤0.05).