Table 4. miRNA-Target gene annotation.
| mi-RNA | Target gene | log2 Fold Change | Gene Description | Biological Process (GO) |
|---|---|---|---|---|
| miR-182-5p | CFL1 | 2.50 | Cofilin 1 | GO:0030043 actin filament fragmentation; GO:0030042 actin filament depolymerization; GO:0044794 positive regulation by host of viral process |
| miR-200c-3p | KIAA1432 | 1.66 | RIC1 homolog, RAB6A GEF complex partner 1 |
GO:0003330 regulation of extracellular matrix constituent secretion; GO:0070278 extracellular matrix constituent secretion; GO:1903053 regulation of extracellular matrix organization |
| miR-199a-5p | ZNF415 | 2.00 | Zinc finger protein 415 | GO:0006357 regulation of transcription by RNA polymerase II; GO:0006366 transcription by RNA polymerase II; GO:0006355 regulation of transcription, DNA-templated |
| miR-193a-5p | MTRNR2L8 | 1.76 | MT-RNR2 like 8 | GO:1900118 negative regulation of execution phase of apoptosis; GO:1900117 regulation of execution phase of apoptosis; GO:2000272 negative regulation of signaling receptor activity |
| miR-155-5p | C9orf78 | 1.53 | chromosome 9 open reading frame 78 | GO:0048024 regulation of mRNA splicing, via spliceosome; GO:0050684 regulation of mRNA processing; GO:0043484 regulation of RNA splicing |
log2 Fold Change: Patients compared to controls.