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. 2023 Mar 20;45(1):2165103. doi: 10.1080/0886022X.2023.2165103

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — TP improved renal function and histopathological injury in DN mice. The DN mouse model was induced by HFD feeding combined with STZ injection. After 12 weeks of treatment with TP, (A) FBG was detected by glucose meter; (B) 24 h UAlb in mice was detected by Bradford method; (C,D) The serum contents of SCr and BUN in mice were detected using an automated biochemical analyzer; (E) The ratio of K/B weight was examined; (F) H&E staining was used to analyze the pathological changes of renal tissues in mice and to quantify the percentage of inflammatory areas; (G) TUNEL staining was used to detect the percentage of apoptosis in renal tissues. Data were expressed as mean ± SD, N = 6. One-way ANOVA was used for data comparison among multiple groups and Tukey’s test was used for the post-hoc test. p-Value was obtained from the bilateral tests. **p < 0.01, ***p < 0.001.