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. 2023 Mar 20;45(1):2165103. doi: 10.1080/0886022X.2023.2165103

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 4. — TP reduced pyroptosis of renal tissue in DN mice by inhibiting the NLRP3 inflammasome pathway. (A) ELISA kits were used to detect the secretion levels of inflammatory cytokines IL-1β and IL-18 in the serum of mice; (B,C) WB was used to detect the protein level of cell pyroptosis markers mediated by NLRP3 inflammasome in mouse kidney tissue. Data were expressed as mean ± SD, N = 6. One-way ANOVA was used for data comparison among multiple groups and Tukey’s test was used for the post-hoc test. **p < 0.01, ***p < 0.001.