Table 1.
Characteristic | Group | No. of Patients |
---|---|---|
Demographic characteristics | ||
Age, y | < 50 | 2 |
50-59 | 3 | |
60-69 | 3 | |
70-79 | 1 | |
Sex | Male | 6 |
Female | 3 | |
BMI, kg/m2 | 25-29.9 | 3 |
30-39.9 | 5 | |
≥ 40 | 1 | |
Comorbidities 4C score44 | 0 | 4 |
1 | 4 | |
3 | 1 | |
Tobacco use history | No tobacco use | 4 |
Former tobacco use | 5 | |
Clinical characteristics on admission | ||
Admission SF ratio | < 200 | 0 |
200-299 | 3 | |
300-399 | 3 | |
≥ 400 | 3 | |
Clinical characteristics during admission | ||
Maximum oxygen requirement during hospital stay | < 28% | 1 |
28%-35% | 4 | |
40% | 2 | |
> 60% | 2 | |
CPAP | 1 | |
ISARIC 4C score44 | 1-4 | 3 |
5-8 | 5 | |
> 8 | 1 | |
Length of stay, d | 1-5 | 4 |
6-9 | 4 | |
> 10 | 1 | |
Maximum National Early Warning Score 2 score45 | 5-6 | 4 |
≥ 7 | 5 | |
Medication during stay | Oral antibiotics | 1 |
IV antibiotics | 2 | |
Dexamethasone | 9 | |
Remdesivir (Gilead Sciences) | 5 | |
Immunomodulation therapy | 3 | |
Convalescent plasma | 2 | |
Colchicine | 2 | |
Aspirin | 3 | |
Included in an interventional study? | 7 | |
Lowest SF ratio during stay | < 200 | 2 |
200-299 | 3 | |
300-399 | 4 | |
≥ 400 | 0 | |
Maximum Fio2 during stay | < 28% | 1 |
28%-35% | 4 | |
40% | 2 | |
> 60% | 2 | |
CPAP | 1 | |
Clinical characteristics postdischarge | ||
MRC Dyspnoea Scale (1-5), 6 wk | 1 | 6 |
2 | 2 | |
Not available | 1 | |
MRC Dyspnoea Scale (1-5), 3 mo | 1 | 7 |
2 | 1 | |
3 | 1 | |
Not available | 0 | |
Readmittance | Yes | 1 for general surgery unrelated to COVID-19 |
No | 8 |
Individuals who formerly used tobacco use all reported ≤ 15 pack y. The pulse oximetry saturation/Fio2 ratio (SF ratio) was calculated by using estimated Fio2 based on flow rate when delivered by nasal cannulae. ISARIC = International Severe Acute Respiratory and Emerging Infection Consortium; MRC = Medical Research Council; pulse oximetry saturation/Fio2 (SF).