Fig. 3.

Plasma TTV load in kidney transplant recipients (KTR) at the time of vaccination (T0). Plasma TTV load in KTR is stratified according to humoral (A) and cellular (B) immune response to vaccination. Humoral and cellular vaccine response were defined as de novo detection of SARS-CoV-2 S1-IgA and/or -IgG (seroconversion) and detection of IFNγ release eight weeks after first vaccination (T1). For statistical analysis, TTV loads were log-transformed and means compared by unpaired t-test. Bars indicate mean. Dotted line indicates limit of detection. Dashed line indicates clinically defined cut-off for reliable prediction of humoral and cellular immune response after vaccination.