Fig. 2. Weekly treatment with drag reducing polymers (DRP) ameliorates β amyloid plaques deposition formation during Alzheimer’s Disease (AD) development.
A. Micrograph of thioflavin S stained saline-treated mouse cortex showing no fluorescence at 4 months and B. Bright β-amyloid plaques fluorescence (thioflavin S) at 12 months of AD development. C. Magnified views of the areas outlined in A and B. D. Micrographs with no β-amyloid plaques visible from the second harmonic generation (SHG) signal at 4 months in DRP-treated mouse brain and E. Bright β-amyloid plaques (SHG) signal at 12 months of AD development. F. Graph showing attenuation of b-amyloid plaques deposition in DRP group. Data presented as mean ± SEM, N=10 per group, *p<0.05, white arrows point plaques depositions.