Table 2.
Multivariable Cox regression analysis to assess the impact of postoperative complications on disease-free interval and overall survival in 1071 patients after resection of pancreatic cancer
| Complications | Patients | Disease-free interval | Overall survival | ||
|---|---|---|---|---|---|
| HR (95% c.i.) | P | HR (95% c.i.) | P | ||
| Pancreatic fistula | 82 (7.7) | 1.30 (0.99 to 1.70) | 0.059 | 1.28 (0.99 to 1.65) | 0.063 |
| Post-pancreatectomy haemorrhage | 50 (4.7) | 1.14 (0.81 to 1.60) | 0.450 | 1.17 (0.86 to 1.61) | 0.316 |
| Biliary leakage | 28 (2.6) | 1.11 (0.70 to 1.76) | 0.653 | 1.07 (0.69 to 1.65) | 0.769 |
| Delayed gastric emptying | 130 (12.1) | 1.05 (0.84 to 1.30) | 0.677 | 0.99 (0.81 to 1.23) | 0.965 |
| Pneumonia | 76 (7.1) | 1.21 (0.92 to 1.58) | 0.174 | 1.28 (0.99 to 1.64) | 0.056 |
| Major complications | 306 (28.6) | 1.22 (1.04 to 1.43) | 0.015 | 1.25 (1.08 to 1.46) | 0.003 |
| Organ failure | 42 (3.9) | 1.86 (1.32 to 2.62) | <0.001 | 1.89 (1.36 to 2.63) | <0.001 |
Values are n (%) unless otherwise indicated. Confounders: age, sex, BMI, Charlson co-morbidity index, tumour size, tumour location, and vascular resection. HR, hazards ratio.