Table 1.
Demographic characteristics of participants included in final analyses; see also Supplementary Fig. 1
| Subgroup | Number of participants (male:female) | Mean age in years (SD, range) |
|---|---|---|
| Control | 149 (51:98) | 59.4 (11.9, 42.0–87.3) |
| MCI | 68 (36:32) | 69.7 (8.0, 53.4–86.4) |
| Alzheimer’s disease | 24 (17:7) | 72.1 (8.0, 55.9–87.8) |
| Atypical Alzheimer’s disease | 2 | |
| Amyotrophic lateral sclerosis-CN | 14 (10:4) | 60.9 (7.1, 42.1–68.2) |
| Amyotrophic lateral sclerosis-CI | 5 | |
| Amyotrophic lateral sclerosis-Other | 16 (8:8) | 60.0 (9.8, 40.1–72.3) |
| bvFTD | 14 (10:4) | 66.6 (8.8, 49.7–77.5) |
| PSP | 8 (4:4) | 70.6 (5.9, 63.5–78.5) |
| bvFTD and PSP | 1 | |
| PNFA | 5 | |
| SD | 3 | |
| CBS | 2 | |
| Parkinson’s disease-CN | 43 (32:11) | 66.1 (6.3, 55.3–80.4) |
| Parkinson’s disease-MCI | 43 (36:7) | 68.2 (6.3, 55.1–81.7) |
| Parkinson’s disease-dementia | 14 (11:3) | 69.1 (8.4, 56.7–84.4) |
| Parkinson’s disease-Other | 6 (5:1) | 73.5 (7.7, 67.6–85.9) |
| Cerebrovascular disease-CN | 69 (46:23) | 68.5 (6.3, 55.0–81.4) |
| Cerebrovascular disease-MCI | 31 (19:12) | 67.6 (7.4, 56.4–84.0) |
| Cerebrovascular disease-dementia | 11 (8:3) | 69.0 (10.1, 57.2–85.4) |
| Cerebrovascular disease-Other | 12 (9:3) | 67.1 (7.1, 58.3–83.4) |
Bolded groups were included in all analyses; italicized groups were included in factor analysis and correlations only; controls were included in parameter-level analysis only. Demographic details are not included for subgroups with ≤5 participants due to confidentiality concerns. bvFTD, behavioural variant frontotemporal dementia; CBS, corticobasal syndrome; CI, cognitively impaired; CN, cognitively normal; MCI, mild cognitive impairment; Other, other cognitive status; PNFA, progressive non-fluent aphasia; PSP, progressive supranuclear palsy; SD, semantic dementia.