| Duplicates removed | 42 |
| Excluded during initial screening (e.g. press releases; news reports; not relevant drug/indication; preclinical study; reviews; case reports; not randomized trial) | 30 |
| Excluded during writing (e.g. reviews; duplicate data; small patient number; nonrandomized/phase I/II trials) | 37 |
| Cited efficacy/tolerability articles | 18 |
| Cited articles not efficacy/tolerability | 22 |
| Search Strategy: EMBASE, MEDLINE and PubMed from 1946 to present. Clinical trial registries/databases and websites were also searched for relevant data. Key words were Ruxolitinib, Opzelura, INCB-18424, topical, cream, atopic dermatitis, eczema, pruritus. Records were limited to those in English language. Searches last updated 5 December 2022 | |
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