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. 2022 Nov 23;198(3):413–421. doi: 10.1007/s10549-022-06792-0

Table 2.

Associations between post-diagnosis sleep duration, sleep quality, sleep patterns, and eating behaviours and cancer outcomes in breast cancer survivorsa

All-cause mortality Breast cancer mortality Breast cancer recurrence Progression-free survival
Exposure: HR (95%CI) Refernces Exposure: HR (95%CI) References Exposure: HR (95%CI) References Exposure: HR (95%CI) References
Sleep duration  ≤ 6 h: 0.95 (0.80–1.13) [31]  ≤ 6 h: 0.83 (0.67–1.04) [31]  ≤ 6 h: 0.93 (0.77–1.12) [31]  < 6 h: 1.45 (0.83–2.54) [37]
 ≤ 6 h: 1.05 (0.88–1.24) [32]  ≤ 6 h: 1.13 (0.86–1.48) [32]
 ≤ 6 h consistent: 0.91 (0.73–1.12) [31]  ≤ 6 h consistent: 0.78 (0.60–1.01) [31]  ≤ 6 h consistent: 0.93 (0.74 -1.17) [31]
 ≤ 6 h inconsistent: 0.79 (0.63–0.98) [31]  ≤ 6 h inconsistent: 0.80 (0.61–1.06) [31]  ≤ 6 h inconsistent: 0.82 (0.64–1.06) [31]
 ≥ 9 h: 1.43 (1.07–1.92) [31]  ≥ 9 h: 1.52 (1.09–2.13) [31]  ≥ 9 h: 1.48 (1.01–2.00) [31]  > 9 h: 2.33 (1.01–5.42) [37]
 ≥ 9 h: 1.37 (1.10–1.71) [32]  ≥ 9 h: 1.46 (1.02–2.07) [32]
 ≥ 9 h consistent: 1.46 (0.97–2.21) [31]  ≥ 9 h consistent: 1.22 (0.75–1.99) [31]  ≥ 9 h consistent:1.30 (0.85–1.98) [31]
 ≥ 9 h inconsistent: 1.47 (1.12–1.93) [31]  ≥ 9 h inconsistent: 1.70 (1.23–2.36) [31]  ≥ 9 h inconsistent: 1.60 (1.18–2.18) [31]
TIB shorter: 0.99 (0.97–1.00) [33]
 ≥ 1 h increase (from pre-to post- dx)b: 1.35 (1.04–1.74) [32]  ≥ 1 h increase (from pre-to post- dx)b: 1.29 (0.84–2.00) [32]
 ≥ 1 h decrease (from pre-to post- dx)b: 1.26 (0.97–1.65) [32] ≥ 1 h decrease (from pre-to post- dx)b: 0.89 (0.55–1.45)
This section should be white  < 6 h or > 9 h: 2.73 (0.99–7.52)c [36]
Sleep quality Difficulty: 1.49 (1.02–2.19) [32] Difficulty: 1.78 (0.94–3.36) [32]
Efficiency (≥ 85%): 0.94 (0.91–0.97) [33] Efficiency (< 85%): 1.65 (0.92–2.92) [37]
Quality (bad/very bad): 3.08 (1.74–5.47) [37]
Quality poor: 0.78 (0.27–2.29)c [36]
Latency: 0.89 (0.75–1.06) [33]
WASO (min): 0.41 (0.25 -0.67) [33]
WASO (%TST): 0.97 (0.96–0.98) [33]
WE (fewer): 0.93 (0.88 -0.98) [33]
WE duration (shorter): 0.29 (0.14–0.58) [33]
Sleep disorders 1.39 (1.04–1.87) [34]
Habitual day time napping 0.94 (0.61–1.44) [37]
Bedtime misalignment d 3.18 (1.32–7.61) [38]
Nightly fasting  < 13 h: 1.22 (0.95–1.56) [35]  < 13 h: 1.21 (0.91–1.60) [35]  < 13 h: 1.36 (1.05–1.76) [35]
Eating episodes per day 0.99 (0.89–1.10) [35] 1.00 (0.89–1.13) [35] 0.97 (0.87–1.08) [35]
Eating after 8PM Yes: 0.97 (0.76–1.24) [35] Yes: 0.98 (0.74–1.28) [35] Yes: 0.97 (0.76–1.24) [35]

aTIB Time In Bed; WASO Wake After Sleep Onset; TST Total Sleep Time; WE Wake Episodes

bChanges in sleep duration from pre-post-diagnosis by either ⩾1 h more (increase) or ⩾1 h less (decrease), versus no change

cMeasured relative risk

dDefined as misalignment of preferred (assessed via Morningness-Eveningness Questionnaire) and habitual bedtime [38]