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Estradiol prevents HFD-induced obesity and reduces HFD intake in female mice. (A) E prevented average body weight gain in mice on a HFD (n = 16/group). (B) E decreased caloric intake per cage in mice on a HFD (n = 4 cages/group). Larger circles show mean (± SEM) and smaller circles show individual data points. *Indicate days when HFD-V mice differ from all other groups. P < 0.05, Tukey’s HSD.
