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. 2023 Mar 23;13:4776. doi: 10.1038/s41598-023-31783-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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HFD increases anxiety-like behavior in the Elevated Plus Maze test. HFD decreased (A) the number of open arm entries, (B) time spent in the open arms (n = 15–16/group). For (A) and (B), a main effect of diet was detected (Kruskal–Wallis, p < 0.05), although individual groups did not differ from each other. (C) Total distance traveled. Black lines show mean (middle line) and 83% CI (whiskers). Green lines show median (middle line) and the 1st (lower line) and the 3rd quartile (upper line). Data points greater than 1.5 times the interquartile range are shown within open circles.