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. 2023 Mar 13;18:100131. doi: 10.1016/j.mbplus.2023.100131

Fig. 5.

Fig. 5

Summary of mechanical properties of decellularized matrices and collagenase digested muscles. (A) A majority of elastic stiffness is maintained in the decellularized diaphragm and soleus. The collagenase digested D2.mdx diaphragm maintains a higher proportion of stiffness than the wildtype. This effect is present in the D2.mdx soleus to a lesser degree. (B) Similar to (A), a majority of elastic stress at 12.5% strain is maintained in the decellularized diaphragm and soleus. The collagenase digested D2.mdx diaphragm maintains a significantly greater proportion of stress than the wildtype. This effect is present in the D2.mdx soleus to a lesser degree. (C) Schematic of the effects of decellularization and collagenase treatments on skeletal muscle mechanics and collagen content. Flat bars represent two-way ANOVA significant main effects by muscle: &p < 0.05; and by genotype: *p < 0.05. Bracketed bars represent post-hoc Sidak test significant differences by muscle: &p < 0.05; and by genotype: *p < 0.05. Panel C of this figure was created using BioRender.com.