Table 1.

Number of published GWAS studies linking polymorphisms (SNPs) in STAT6 to common allergic diseases in the population

Phenotype	Number of published associations	References
Asthmaa	14	Daya et al., 2019; Demenais et al., 2018; Ferreira et al., 2019; Han et al., 2020; Johansson et al., 2019; Olafsdottir et al., 2020; Pickrell et al., 2016; Pividori et al., 2019; Sakaue et al., 2021; Shrine et al., 2019; Valette et al., 2021; Zhu et al., 2020; Zhu et al., 2018; Zhu et al., 2019
Eosinophil count	7	Astle et al., 2016; Chen et al., 2020; Höglund et al., 2022; Kachuri et al., 2021; Kichaev et al., 2019; Sakaue et al., 2021; Vuckovic et al., 2020
Allergic disease	3	Ferreira et al., 2017; Ferreira et al., 2020; Zhu et al., 2018
Atopic dermatitis/eczema	3	Johansson et al., 2019; Kichaev et al., 2019; Tanaka et al., 2021
Serum IgE level	2	Daya et al., 2021; Granada et al., 2012
Allergic sensitization	2	Bønnelykke et al., 2013; Waage et al., 2018
Allergic rhinitis	1	Johansson et al., 2019
Eosinophilic gastrointestinal disorders	1	Sleiman et al., 2014

Significant genome-wide associations (P < 5 × 10⁻⁸) between STAT6 SNPs and all relevant allergic traits were obtained through the National Human Genome Research Institute–European Bioinformatics Institute GWAS Catalog (https://www.ebi.ac.uk/gwas/).

^aIncludes asthma, childhood-onset asthma, adult-onset asthma, and atopic asthma.