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. 2023 Mar 23;6(3):e234415. doi: 10.1001/jamanetworkopen.2023.4415

Table 2. Sociodemographic and Baseline Clinical Characteristics of Mothers and Offspring With 18-Month Follow-up Data.

Characteristic Maternal SARS-CoV-2 status during pregnancya P valueb
Negative (n = 13 452) Positive (n = 555)
Maternal age, mean (SD), y 33.0 (4.9) 31.1 (5.8) <.001
Maternal race
Asian 1375 (10.2) 29 (5.2) <.001
Black 1153 (8.6) 102 (18.4)
White 9399 (69.9) 231 (41.6)
Otherc 1188 (8.8) 161 (29.0)
Unknown 337 (2.5) 32 (5.8)
Maternal ethnicityd
Hispanic 1796 (13.4) 234 (42.2) <.001
Non-Hispanic 11 266 (83.7) 295 (53.2)
Unavailable 386 (2.9) 26 (4.7)
Maternal public insurance 2411 (17.9) 286 (51.5) <.001
Trimester of maternal SARS-CoV-2 infectione
First NA 46 (8.3) >.99
Second NA 114 (20.5)
Third NA 386 (69.5)
Unknown NA 9 (1.6)
Delivery hospital type
Academic medical center 7901 (58.7) 397 (71.5) <.001
Community hospital 5551 (41.3) 158 (28.5)
Delivery method
Cesarean 4456 (33.1) 190 (34.2) .59
Vaginal 8996 (66.9) 365 (65.8)
Multiple births 843 (6.3) 46 (8.3) .056
Delivery admission length of stay, median (IQR), d 3.00 (2.00-4.00) 3.00 (2.00-4.00) .63
Birth
Preterm 1333 (9.9) 82 (14.8) <.001
Term 12 119 (90.1) 473 (85.2)
Offspring sex
Female 6613 (49.2) 266 (47.9) .57
Male 6839 (50.8) 289 (52.1)

Abbreviation: NA, not applicable.

a

Unless otherwise indicated, data are expressed as No. (%) of mothers of live offspring. Percentages have been rounded and may not total 100. Data were collected between March 1, 2020, and May 31, 2021.

b

Calculated using the Wilcoxon rank sum test, Pearson χ2 test, or Fisher exact test.

c

Includes American Indian or Alaska Native, Native Hawaiian or other Pacific Islander, and more than 1 race or ethnicity.

d

Ethnicity was unknown for 4 mothers in the COVID-19–negative group.

e

Trimester of infection was unknown for 9 mothers in the COVID-19–positive group.