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. 2023 Feb 2;11(3):638–648. doi: 10.14218/JCTH.2022.00309

Table 3. Area under the curve (AUC) and correlation of VOCs with blood metrics.

VOC Identity AUC Correlation (coefficient r, p-value)
Bilirubin Albumin PT-INR
VOC1 2-pentanone 0.82 0.548, 0.01 −0.346, 0.014 0.347, 0.013
VOC2 Eucalyptol 0.80 0.258, 0.07 −0.348, 0.013 0.264, 0.064
VOC3 Limonene 0.79 0.516, 0.01 −0.487, 0.01 0.178, 0.216
VOC4 Dimethyl selenide 0.76 −0.012, 0.936 0.492, 0.01 −0.135, 0.352
VOC5 Terpene 0.72 0.415, 0.003 −0.552, 0.01 0.309, 0.029
VOC6 2-Pentanone (m/z 43.02369) 0.72 0.308, 0.03 −0.196, 0.173 −0.022, 0.881
VOC7 Terpene 0.71 0.344, 0.014 −0.236, 0.098 −0.112, 0.441
VOC8 Terpene 0.70 0.368, 0.009 −0.388, 0.005 0.338, 0.016
VOC9 Unknown 0.69 0.136, 0.346 0.067, 0.642 0.0, 1.0
VOC10 Unknown 0.68 0.028, 0.845 0.267, 0.061 −0.014, 0.921
VOC11 Terpene 0.67 0.177, 0.22 −0.412, 0.003 −0.077, 0.594

VOC, volatile organic compound; AUC, area under the curve; PT-INR, prothrombin time-international normalized ratio.