Figure 5.
Out-of-field recurrence in Subject 1. Imaging of the sMRI, T1w-CE, and T2 FLAIR at the recurrence date (15 months post-RT) with the site of tumor progression indicated by the white arrow on sMRI. The green contour shows the additional 30.50 cc metabolically active mass at the Cho/NAA ≥ 2x threshold on the sMRI. The spectra identified by the boxed ROI on the sMRI map shows clearly elevated Cho and decreased NAA (gray arrows), corresponding to presence of tumor. The lesion is not identifiable with confidence on the T1w-CE and is better seen on sMRI than T2 FLAIR.