Table 3.
Secondary outcomes.
| Outcome | Testosterone | Placebo | Effect Size [CI] | Overall p-Value | Heterogeneity |
|---|---|---|---|---|---|
| Total cholesterol | −0.71 [−1.22, −0.21] | 0.10 [−016, 0.35] | −0.32 [−0.64, 0.00] | 0.05 | 87.2 |
| Triglyceride | −0.47 [−0.75, −0.20] | 0.03 [−021, 0.27] | −0.23 [−0.47, 0.00] | 0.05 | 86.6 |
| LDL cholesterol | −0.20 [−1.12, 0.73] | 0.17 [−0.13, 0.46] | −0.02 [−0.52, 0.48] | 0.94 | 0 |
| HDL cholesterol | 0.10 [0.01, 0.20] | 0.03 [−0.07, 0.13] | 0.07 [0.00, 0.13] | 0.04 | 8.7 |
| Body fat | −0.98 [−1.59, −0.38] | −0.54 [−1.12, 0.03] | −0.75 [−1.17, −0.34] | 0.0004 | 6.4 |
| Waist circumference | −3.98 [−6.48, −1.48] | 0.73 [−1.44, 2.89] | −1.68 [3.43, 0.07] | 0.06 | 87.1 |
| BMI | −1.12 [−2.98, 0.74] | 0.05 [−0.51, 0.61] | −0.56 [−1.48, 0.36] | 0.23 | 27.5 |
| SBP | −0.90 [−12.07, 10.26] | −0.19 [−3.19, 2.81] | −0.51 [−6.24, 5.11] | 0.85 | 0 |
| DBP | −3.09 [−5.52, −0.65] | −0.23 [−1.98, 1.52] | −1.68 [−3.16, −0.21] | 0.03 | 71.3 |
| IIEF | 6.98 [3.62, 10.33] | −3.94 [−10.97, 3.10] | 1.66 [−6.75, 10.06] | 0.70 | 86.7 |
| AMS | −16.80 [−26.96, −6.64] | 4.90 [−9.05, 18.85] | −5.94 [−21.87, 9.98] | 0.46 | 83.5 |
CI: confidence interval, LDL: low-density lipoprotein, HDL: high-density lipoprotein, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, IIEF: international index of erectile function, AMS: aging male score.