Table. Tuberculosis cases involving Mycobacterium caprae , Andalusia, 2003–2022 (n = 30).
| ID patient | Year | Origin | Risk factor for M. caprae infectiona | Mirutyping loci | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M02 | M20 | M23 | M24 | M27 | M39 | M4 | M26 | M40 | M10 | M16 | M31 | M42 | M43 | ETRA | 47 | 52 | 53 | Qub 11b |
1995 | Qub 26 |
M46 | M48 | M49 | ||||
| 118 | 2003 | Spain (Almería) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 1401 | 2011 | Spain (Almería) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 1478.1 (Farmer A, first episode) | 2011 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 1478.2 (Farmer A, second episode) | 2020 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 2672 (Farmer B) | 2020 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 2142 (sibling A) | 2016 | Spain (Almería) | Consumer of unpasteurised milk | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 2319 (sibling B) | 2017 | Spain (Almería) | Consumer of unpasteurised milk | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 1300 | 2010 | Spain (Almería) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 1 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 1485 | 2011 | Mauritania | Exposure to goats | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 1 | 2 | 4 | 1 | 2 | 3 | 3 | 2 |
| 1986 | 2015 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 1 | 5 | 4 | 4 | 1 | 2 | 8 | 1 | 2 | 3 | 3 | 2 |
| 2127 | 2016 | Mali | Exposure to cattle | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 1 | 2 | 4 | 1 | 2 | 3 | 3 | 2 |
| 2309 | 2017 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 |
| 2486 | 2019 | Spain (Almería) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 1 | 2 | 4 | 1 | 2 | 3 | 3 | 2 |
| 2929 | 2021 | Spain (Almería) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 |
| 3006 | 2017 | Spain (Malaga) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3007 | 2018 | Spain (Malaga) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3008 | 2018 | Spain (Malaga) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 4 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 |
| 3010 | 2019 | Western Sahara | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 4 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 2 | 2 |
| 3011 | 2021 | Spain (Sevilla) | Professional exposure | 2 | 2 | 3 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3012 | 2021 | Spain (Malaga) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3013 | 2021 | Spain (Malaga) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 1 | 2 | 4 | 1 | 2 | 3 | 3 | 2 |
| 3015 | 2015 | Spain (Sevilla) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3016 | 2017 | Spain (Sevilla) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3040 | 2022 | Spain (Córdoba) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3041 | 2019 | Spain (Córdoba) | Exposure to goats | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3045 | 2011 | Lithuania | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 5 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3046 | 2013 | Morocco | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 6 | 4 | 5 | 2 | 5 | 4 | 4 | 1 | 2 | 4 | 1 | 2 | 3 | 2 | 2 |
| 3048 | 2018 | Spain (Sevilla) | Professional exposure | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3049 | 2020 | Spain (Sevilla) | Unknown | 2 | 2 | 4 | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
| 3050 | 2018 | Spain (Sevilla) | Professional exposure | 2 | 2 | NA | 2 | 3 | 2 | 4 | 5 | 2 | 3 | 4 | 2 | 3 | 5 | 4 | 4 | 1 | 2 | 2 | 1 | 2 | 3 | 3 | 2 |
NA: not available.
a We differentiate between professional exposure and non-systematic exposure (e.g. farm visitors).
Bold numbers represent the allele diversity identified in certain MIRU-VNTR loci with respect to the majority allele among the isolates in the study.