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. 2023 Mar 24;23(6):744–758. doi: 10.1016/j.ajt.2023.03.014

Figure 4.

Figure 4

Response patterns following third mRNA vaccine doses: correlation of SARS-CoV-2 antibody and T cell responses. Scatterplot of anti-receptor binding domain (RBD) level and dimensions of SARS-CoV-2 T cell receptor expansion (spike-specific CD4+ and CD8+ breadth and depth) on the logarithmic scale at day 30 post vaccination among kidney transplant recipients (A, n = 55) and healthy controls (B, n = 19). Data points are colorized by response pattern, (+)/(-) anti- RBD and (+)/(-)T-MAP (SARS-CoV-2-reactive T cell repertoire). Trend lines visualize correlation between vaccine responses in participants with detectable signatures (i.e., (+)anti-RBD and categorizable T cell receptor repertoire).