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. 2023 Mar 20;15(1):2186114. doi: 10.1080/19490976.2023.2186114

Figure 4.

Figure 4.

C.B boosts 5-FU treatment efficacy in mouse xenograft CRC model.

(a) Schematic overview of in vivo experiment and representative images of HCT116 cells xenograft tumor in control (n = 5), C.B CM (n = 5), 5-FU (n = 5), and C.B CM + 5-FU (n = 5) groups.

(b) Tumor volumes of indicated groups.

(c) Tumor weights of indicated groups.

(d) Represent IHC images and quantification analysis of Ki67, CASPASE 3, TYMS and MYC from indicated groups. Staining intensity was quantitated. Scale bar: 10×, 100 μM; 40×, 25 μM. Data are presented as mean ± SEM. ns, no significance; *, p < 0.05; **, p < 0.01; ***, p < 0.001; one-way ANOVA test and two-way ANOVA test.