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. 2023 Mar 14;19(3):e1010665. doi: 10.1371/journal.pgen.1010665

Fig 1. Strains expressing ion channel mutants in RIS.

Fig 1

A) Scheme of the genetic design of the different RIS potassium channel mutant transgenes. B-D) Localization and expression of mKate2, which is translationally fused to the ion channels, in the different inactivation strains. E) Schematic representation of the genetic design of the RIS sodium channel mutant transgenes. F) Quantification of the expression levels of UNC-58gf::mKate2 in the two RIS overactivation strains. ***p<0.001, Welch test. G) Localization and expression of the strong overactivation strain (RIS::unc-58gf(strong)). H) Localization and expression of the weak overactivation strain (RIS::unc-58gf(weak)).