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. 2023 Mar 14;19(3):e1010665. doi: 10.1371/journal.pgen.1010665

Fig 9. RIS::unc-58gf(strong) is refractory to optogenetic activation of RIS.

Fig 9

A) Optogenetic activation of RIS during the stimulation time (minute 1–2) leads to an increase of RIS activity and reduced mobility in wild-type worms but it does not affect the strong RIS activation strain. RIS speed was measured. A statistical comparison was made between baseline (0-1min) and stimulation (1-2min). n.s. p>0.05, **p<0.01, ***p<0.001, Wilcoxon signed rank test. B) Control for the optogenetic experiment. Without ATR treatment, neither the wild type nor the strong RIS activation strain, shows a response to green light. N.s. p>0.05, Wilcoxon signed rank test.