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. 2023 Mar 24;14:243–257. doi: 10.18632/oncotarget.28390

Figure 2. Concentration-response curves of PCAIs against MDA-MB-468 cells.

Figure 2

Cells were treated with varying concentrations of NSL-YHJ-2-27 (potent compound) or NSL-YHJ-2-62 (compound lacking the polyisoprenyl moiety used as control) at the onset and after 24 h. After 48 h, resazurin reduction assay was performed to determine the residual cell viability. The EC50 values were determined by plotting the relative fluorescence intensities (expressed percentages of the control values) against concentration in a non-linear regression curve fit using GraphPad Prism version 8.0 for Windows (San Diego, CA, USA).