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. 2023 Mar 24;149(10):7493–7503. doi: 10.1007/s00432-023-04707-0

Table 2.

Incident malignant neoplasms as well as incident carcinoma in situ in total and by tumor site during the COVID-19 pandemic (March 2020 to February 2021) compared to the pre-pandemic period (March 2019 to February 2020)

Tumor site (ICD-10) Pre-pandemic period: cases Pandemic period: cases Difference (% [95% CI])a
Malignant neoplasms
 All sites (C00-C97 without C44 and C77-C79) 42,857 39,980 − 2877 (− 6.7 [− 8.7; − 4.7])*
 Breast (C50) 8703 8278 − 425 (− 4.9 [− 9.3; − 0.2])*
 Prostate (C61) 6649 5974 − 675 (− 10.2 [− 15.0; − 5.0])*
 Colon (C18) 4032 3568 − 464 (− 11.5 [− 17.6; − 4.9])*
 Lung (C34) 3536 3294 − 242 (− 6.8 [− 13.6; 0.5])
 Rectum (C19/C20) 2095 1772 − 323 (− 15.4 [− 23.5; − 6.5])*
 Stomach (C16) 1450 1393 − 57 (− 3.9 [− 14.5; 8.0])
 Bladder (C67) 1359 1347 − 12 (− 0.9 [− 12.1; 11.8])
 Non-Hodgkin lymphoma (C82-C88, C96) 1309 1307 − 2 (− 0.2 [− 11.6; 12.8])
 Corpus uteri (C54/C55) 1265 1167 − 98 (− 7.7 [− 18.7; 4.7])
 Lip, oral cavity, and pharynx (C00-C14) 1197 1110 − 87 (− 7.3 [− 18.6; 5.6])
 Kidney (C64) 1197 1092 − 105 (− 8.8 [− 19.9; 4.0])
 Skin/Melanoma (C43) 1112 939 − 173 (− 15.6 [− 26.5; − 3.0])*
 Pancreas (C25) 999 1039 40 (4.0 [− 9.4; 19.4])
 Leukemia (C91-C95) 633 563 − 70 (− 11.1 [− 25.8; 6.6])
 Liver (C22) 630 554 − 76 (− 12.1 [− 26.7; 5.5])
 Esophagus (C15) 610 616 6 (1.0 [− 15.5; 20.7])
 Ovary (C56) 608 683 75 (12.3 [− 5.6; 33.7])
 Cervix uteri (C53) 463 508 45 (9.7 [− 10.2; 34.1])
 Other 5010 4,776 − 234 (− 4.7 [− 10.5; 1.5])
Carcinoma in situ
 All sites (D00-D09 without D04) 4080 4939 859 (21.1 [13.3; 29.3])*
 Bladder (D09.0) 1101 1081 − 20 (− 1.8 [− 14.1; 12.2])
 Cervix uteri (D06) 1042 2180 1,138 (109.2 [86.0; 135.3])*
 Breast (D05) 905 771 − 134 (− 14.8 [− 26.9; − 0.7])*
 Colon (D01.0) 283 173 − 110 (− 38.9 [− 54.8; − 17.4])*
 Skin/Melanoma (D03) 280 219 − 61 (− 21.8 [− 41.0; 3.7])
 Rectum (D01.1/D01.2) 99 72 − 27 (− 27.3 [− 55.2; 17.9])
 Other 370 443 73 (19.7% [− 3.9%; 49.2%])

ICD-10 international statistical classification of diseases and related health problems, tenth revision, CI confidence interval

*Indicates that the relative change is significantly different from zero with a significance level of 5% with Bonferroni correction (effective α error of 0.18%)

aCI with Bonferroni correction (effective CI of 99.82%)