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. 2023 Mar 9;12:e77507. doi: 10.7554/eLife.77507

Figure 3. Differential expression analysis between two groups of samples classified according to a chromosomal instability (CIN)-score threshold.

Figure 3.

The CIN-score function allows the graphic visualization of CIN-scores for all samples in a study. A CIN-score threshold selected by the user can be depicted on the graph (red dotted line). The CIN-score threshold selected by the user can be used in the DEG tab to define the two-group comparison. Stages 1–9 represent the nine developmental stages of LUSC as described in Mascaux et al., 2019 (GSE33479). CIN70, CIN25, and CIN5 can be used in the DEG tab. Sample sizes: n=12 (stage 7), n=13 (stages 1, 5, 6 and 8), n=14 (stages 2 and 9), n=15 (stages 3 and 4). Boxplots show median and upper/lower quartile. Whiskers show the smallest and largest observations within 1.5× IQR.